Berries
Billbery
Introduction to Bilberry
Bilberries (Vaccinium myrtillus) are small, dark-blue fruits native to Europe and closely related to blueberries. Known for their high concentration of anthocyanins and other polyphenols, bilberries are recognized for their role in supporting overall wellness, including cognitive function. Axolt includes bilberry extract in its formulations as a key source of polyphenols. Each daily dose of Axolt contains 50 mg of bilberry extract, alongside Gotu Kola, Greek Mountain Tea, Spearmint Extract, Turmeric, and Aronia.
Role in Brain Health
Anthocyanins, the primary bioactive compounds in bilberries, play a crucial role in promoting brain health (3).
These polyphenols support neuronal integrity by reducing oxidative stress and inflammation, both of which are key contributors to cognitive decline (2)."
Studies have shown that bilberry anthocyanins are linked to neural communication pathways involved in learning and memory. (4).
Bilberries also influence vascular health by improving blood flow and reducing vascular inflammation (5).
This, in turn, contributes to the efficient delivery of oxygen and nutrients to the body, including the brain (4).
Core Benefits for the Brain
- Supports neural pathways associated with memory and learning (1, 2, 4).
- Reduces oxidative stress and neuroinflammation, protecting neurons (2).
- Improves blood flow to the brain, indirectly enhancing cognitive function (4).
- May help delay age-related cognitive decline through its polyphenol activity (3, 4).
Axolt Formulation Principles
Axolt delivers over 1,000 mg of polyphenols per daily dose, sourced from the finest suppliers with scientifically validated claims regarding content and brain health benefits.
Bilberry contributes a substantial portion of these polyphenols, enhancing the formulation's potency.
Our systemic approach ensures comprehensive support for all key biological pathways known to be vital for brain health, reflecting our unwavering commitment to being the world’s leading brain health supplement.
Resources
1. Chu WK, Cheung SCM, Lau RAW, Benzie IFF. Bilberry (Vaccinium myrtillus L.). In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd ed. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 4. PMID: 22593936.
2. Sharma A, Lee HJ. Anti-Inflammatory Activity of Bilberry (Vaccinium myrtillus L.). Curr Issues Mol Biol. 2022 Sep 30;44(10):4570-4583. doi: 10.3390/cimb44100313. PMID: 36286028; PMCID: PMC9601269.
3. Smeriglio A, Monteleone D, Trombetta D. Health effects of Vaccinium myrtillus L.: evaluation of efficacy and technological strategies for preservation of active ingredients. Mini Rev Med Chem. 2014;14(7):567-84. doi: 10.2174/1389557514666140722083034. PMID: 25052033.
4. Vauzour D, Rendeiro C, D'Amato A, Waffo-Téguo P, Richard T, Mérillon JM, Pontifex MG, Connell E, Müller M, Butler LT, Williams CM, Spencer JPE. Anthocyanins Promote Learning through Modulation of Synaptic Plasticity Related Proteins in an Animal Model of Ageing. Antioxidants (Basel). 2021 Jul 31;10(8):1235. doi: 10.3390/antiox10081235. PMID: 34439483; PMCID: PMC8388918.
5. Chu W, Cheung SCM, Lau RAW, et al. Bilberry (Vaccinium myrtillus L.) In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 4. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92770/
