Berries
Aronia Brainberry
Introduction to Aronia
Aronia berries, also known as chokeberries, are nutrient-rich fruits abundant in polyphenols and other bioactive compounds (1). These berries are particularly renowned for their ability to support brain health and cognitive function.
Axolt incorporates clinically validated Brainberry®, a premium Aronia extract, into its formulations to help maintain neuronal health and support cognitive performance (https://brainberry.eu).
Each serving of Axolt contains 65 mg of Brainberry®, standardized for high levels of cyanidin-3-O-galactoside, a potent anthocyanin shown in clinical studies to to support focus and psychomotor performance.
The Brainberry® extract is derived from the Nero Eggert variety of fresh Aronia berries, naturally rich in cyanidin glycosides. These flavonoids are recognized for their role in supporting vascular function, which contributes to brain health (3, 4).
Role in Brain Health
Aronia berries, particularly in the form of Brainberry®, are a rich source of polyphenols such as anthocyanins and procyanidins, which play a direct role in supporting brain health.
These compounds contribute to normal oxidative and inflammatory processes in the brain, supporting neuronal integrity and synaptic function (1). Preliminary research on Brainberry® suggests it may support psychomotor performance after consistent use (5). Brainberry® further contributes to brain health through its positive impact on vascular function (5). By contributing to healthy blood flow, it ensures optimal delivery of oxygen and nutrients to brain tissues, essential for maintaining cognitive function (5).
The clinically validated benefits of Brainberry®'s properties make it a beneficial ingredient for supporting memory, mental clarity, and overall cognitive performance.
Axolt Formulation Principles
The inclusion of aronia in Axolt’s formulations aligns with the brand’s focus on synergistic, bioavailable, and body-native ingredients. By selecting aronia extracts with high concentrations of polyphenols, Axolt ensures the brain-supportive properties of these berries are fully utilized. This comprehensive approach supports aronia’s role in maintaining cognitive health.
Core Benefits and Claims
- Supports Synaptic Function: Supports memory and cognitive flexibility (5).
- Contributes to Psychomotor Performance: Supports task performance. (5)
- Supports Oxidative and Inflammatory Processes: Helps maintain neuronal health (2)
- Supports Vascular Health: Contributes to healthy blood flow to the brain. (5)
- Supports Mental Clarity: Helps with focus and reducing mental fatigue. (6)
Resources
1. Saracila M, Untea AE, Oancea AG, Varzaru I, Vlaicu PA. Comparative Analysis of Black Chokeberry (Aronia melanocarpa L.) Fruit, Leaves, and Pomace for Their Phytochemical Composition, Antioxidant Potential, and Polyphenol Bioaccessibility. Foods. 2024 Jun 13;13(12):1856. doi: 10.3390/foods13121856. PMID: 38928798; PMCID: PMC11202527.
2. Ruczaj A, Brzóska MM, Rogalska J. The Protective Impact of Aronia melanocarpa L. Berries Extract against Prooxidative Cadmium Action in the Brain-A Study in an In Vivo Model of Current Environmental Human Exposure to This Harmful Element. Nutrients. 2024 Feb 9;16(4):502. doi: 10.3390/nu16040502. PMID: 38398826; PMCID: PMC10891719.
3. Li, B., Jin, C., Shu, C., Jiang, H., Xu, H., Tian, J., Gao, N., Liu, S., Chen, W., Cui, X., Wang, Y., Lang, Y., & Li, Z. (2024). Polyphenol components in black chokeberry (Aronia melanocarpa) as clinically proven diseases control factors—an overview. Food Science and Human Wellness, 13(3), 1152–1167. https://doi.org/10.26599/fshw.2022.9250096
4. Cui, Y., Lin, Y., Meng, X., Ma, J., Deng, H., Liu, X., He, X., & Zhao, J. (2021). Cyanidin-3-galactoside from Aronia melanocarpa ameliorates PM10 induced pulmonary injury by modulating M1/M2 macrophage polarization and NRF2/Sirt1 MAPK signaling. Journal of Functional Foods, 85, 104363. https://doi.org/10.1016/j.jff.2021.104363
5. Ahles, S., Joris, P.J. & Plat, J. Short-term Aronia melanocarpa extract supplementation improves cognitive performance: a randomized, double-blind, placebo-controlled cross-over study in healthy young adults. Eur J Nutr 63, 1545–1553 (2024). https://doi.org/10.1007/s00394-024-03381-3
6. Krikorian R., Shidler M.D., Nash T.A., Kalt W., Vinqvist-Tymchuk M.R., Shukitt-Hale B., Joseph J.A. Blueberry supplementation improves memory in older adults. J. Agric. Food Chem. 2010;58:3996–4000. doi: 10.1021/jf9029332
